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Article

Allelic imbalance at the HER2/TOP2A locus in breast cancer.

Diagnostic pathology - 29 May 2015

Huijsmans Cornelis J J, van den Brule Adriaan J C, Rigter Henny, Poodt Jeroen, van der Linden Johannes C, Savelkoul Paul H M, Hilbink Mirrian, Hermans Mirjam H A

Abstract excerpt

BACKGROUND: Breast cancer is a heterogeneous disease with various histological features and molecular markers. These are utilized for the prediction of clinical outcome and therapeutic decision making. In addition to well established markers such as HER2 overexpression and estrogen and progesterone receptor (ER and PR) status, chromosomal instability is evolving as an important hallmark of cancers. The HER2/TOP2A...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26022247
DOI: 10.1186/s13000-015-0289-x
PMCID: PMC4448206

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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