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Article

Changes in allelic imbalances in locally advanced breast cancers after chemotherapy.

British journal of cancer - 22 Oct 2007

Varna M, Soliman H, Feugeas J-P, Turpin E, Chapelin D, Legrès L, Plassa L-F, de Roquancourt A, Espié M, Misset J-L, Janin A, de Thé H, Bertheau P

Abstract excerpt

In advanced breast cancers, TP53 mutation is highly predictive of complete response to high-dose epirubicin/cyclophosphamide chemotherapy. In these tumours with an altered control of genomic stability, accumulation of chemotherapy-induced genetic alterations may contribute to cell death and accou...

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Identifiers

PMID: 17876337
DOI: 10.1038/sj.bjc.6603937
PMCID: PMC2360433

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17876337-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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