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Article

Amplification of HER2 is a marker for global genomic instability.

BMC cancer - 14 Oct 2008

Ellsworth Rachel E, Ellsworth Darrell L, Patney Heather L, Deyarmin Brenda, Love Brad, Hooke Jeffrey A, Shriver Craig D

Abstract excerpt

BACKGROUND: Genomic alterations of the proto-oncogene c-erbB-2 (HER-2/neu) are associated with aggressive behavior and poor prognosis in patients with breast cancer. The variable clinical outcomes seen in patients with similar HER2 status, given similar treatments, suggests that the effects of am...

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Identifiers

PMID: 18854030
DOI: 10.1186/1471-2407-8-297
PMCID: PMC2571108

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18854030-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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