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Allelic imbalance of HER2 variant in sporadic breast and ovarian cancer.

Cancer genetics and cytogenetics - 1 May 2006

Puputti Marjut, Sihto Harri, Isola Jorma, Butzow Ralf, Joensuu Heikki, Nupponen Nina N

Abstract excerpt

Both breast and ovarian cancers are associated with HER2 receptor activation, which usually results from receptor overexpression and/or gene amplification. The HER-2 gene harbors a polymorphism at codon 655 (GTC/valine to ATC/isoleucine) in the transmembrane domain region, which has been associated with an elevated risk of breast cancer. The objective of this study was to determine whether the polymorphism is...

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Share to Aged, 80 and over
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Neoplasm

Share to Genes, erbB-2

Share to Nucleic Acid Amplification Techniques

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Source

Identifiers

PMID: 16682283
DOI: 10.1016/j.cancergencyto.2004.09.023

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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