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Article

Aberrations of <i>ERBB2</i> and <i>TOP2A</i> genes in breast cancer

18 Nov 2009

Abstract excerpt

Copy number changes in TOP2A have frequently been linked to ERBB2 (HER2) amplified breast cancers. To study this relationship, copy number changes of ERBB2 and TOP2A were investigated by fluorescence in situ hybridization (FISH) in two cell lines; one characterized by having amplification of both genes and the other by having amplification of ERBB2 and deletion of TOP2A. The characteristics are compared to...

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PMID: 19945923
DOI: 10.1016/j.molonc.2009.11.001

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Aberrations of <i>ERBB2</i> and <i>TOP2A</i> genes in breast cancerPMID 19945923Read ↗

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