Influence of MTHFD1L variants on the susceptibility to hypertension in the Chinese Han population.

doi:10.1080/07853890.2025.2553213

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Article

Influence of MTHFD1L variants on the susceptibility to hypertension in the Chinese Han population.

Annals of medicine - 1 Dec 2026

Li Quanni, Wang Luyao, Li Xiaobo, Xie Pingdong, Zhang Yunjun, Zhou Xiaoli, Ding Yipeng, Tong Shan

Abstract excerpt

BACKGROUND: MTHFD1L gene encoded a mitochondrial enzyme that plays a crucial role in the production of tetrahydrofolate within the mitochondria. However, research on the association between MTHFD1L gene variations and hypertension risk is limited. METHODS: This study included a total of 723 participants, consisting of 367 healthy individuals and 356 individuals diagnosed with hypertension. Four single nucleotide...

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Identifiers

PMID: 41943906
DOI: 10.1080/07853890.2025.2553213
PMCID: PMC13059031

Genes

MTHFD1L

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PubMed metadata and Literature Corpus relationships.