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Article

Mapping the genetic architecture of gene regulation in whole blood.

PloS one - 1 Jan 2014

Schramm Katharina, Marzi Carola, Schurmann Claudia, Carstensen Maren, Reinmaa Eva, Biffar Reiner, Eckstein Gertrud, Gieger Christian, Grabe Hans-Jörgen, Homuth Georg, Kastenmüller Gabriele, Mägi Reedik, Metspalu Andres, Mihailov Evelin, Peters Annette, Petersmann Astrid, Roden Michael, Strauch Konstantin, Suhre Karsten, Teumer Alexander, Völker Uwe, Völzke Henry, Wang-Sattler Rui, Waldenberger Melanie, Meitinger Thomas, Illig Thomas, Herder Christian, Grallert Harald, Prokisch Holger

Abstract excerpt

BACKGROUND: We aimed to assess whether whole blood expression quantitative trait loci (eQTLs) with effects in cis and trans are robust and can be used to identify regulatory pathways affecting disease susceptibility. MATERIALS AND METHODS: We performed whole-genome eQTL analyses in 890 participan...

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Identifiers

PMID: 24740359
DOI: 10.1371/journal.pone.0093844
PMCID: PMC3989189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24740359-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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