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Article

Diminished levels of the soluble form of RAGE are related to poor survival in malignant melanoma.

International journal of cancer - 1 Dec 2015

Wagner Nikolaus B, Weide Benjamin, Reith Maike, Tarnanidis Kathrin, Kehrel Coretta, Lichtenberger Ramtin, Pflugfelder Annette, Herpel Esther, Eubel Jana, Ikenberg Kristian, Busch Christian, Holland-Letz Tim, Naeher Helmut, Garbe Claus, Umansky Viktor, Enk Alexander, Utikal Jochen, Gebhardt Christoffer

Abstract excerpt

RAGE is a central driver of tumorigenesis by sustaining an inflammatory tumor microenvironment. This study links the soluble forms of RAGE (sRAGE and esRAGE) with clinical outcome of melanoma patients. Moreover, tissue expression of RAGE was analyzed using immunohistochemistry on two independent tissue microarrays (TMA) containing 35 or 257 primary melanomas, and 41 or 22 benign nevi, respectively. Serum...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26018980
DOI: 10.1002/ijc.29619

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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