Article
Association of RAGE polymorphisms and cancer risk: a meta-analysis of 27 studies.
Medical oncology (Northwood, London, England) - 1 Feb 2015
Xia Wenjie, Xu Youtao, Mao Qixing, Dong Gaochao, Shi Run, Wang Jie, Zheng YanYan, Xu Lin, Jiang Feng
Abstract excerpt
The receptor for advanced glycation end products (RAGE), a member of immunoglobulin superfamily, has been proved to stimulate survival, growth, and metastatic spread of cancers cells. Evidence suggested that the 82G/S, -374T/A, and -429T/C polymorphisms in RAGE promoter region might affect the risk of cancer; however, data from epidemiological studies showed conflicting results that remain to be further...
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