Article
Genetically lowered concentrations of circulating sRAGE might cause an increased risk of cancer: Meta-analysis using Mendelian randomization.
The Journal of international medical research - 1 Apr 2016
Huang Qingxian, Mi Jia, Wang Xizhen, Liu Fang, Wang Dan, Yan Dong, Wang Bin, Zhang Shuping, Tian Geng
Abstract excerpt
OBJECTIVES: To undertake a systematic meta-analysis of all variants in the gene encoding receptor for advanced glycation end products (RAGE) to summarize their associations with cancer risk and changes in the levels of circulating soluble RAGE (sRAGE), with the aim of determining possible causality between circulating sRAGE and cancer risk. METHODS: Articles written in English were retrieved from MEDLINE® and...
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