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Article

RAGE overexpression confers a metastatic phenotype to the WM115 human primary melanoma cell line.

Biochimica et biophysica acta - 1 Jul 2014

Meghnani Varsha, Vetter Stefan W, Leclerc Estelle

Abstract excerpt

The formation of melanoma metastases from primary tumor cells is a complex phenomenon that involves the regulation of multiple genes. We have previously shown that the receptor for advanced glycation end products (RAGE) was up-regulated in late metastatic stages of melanoma patient samples and we hypothesized that up-regulation of RAGE in cells forming a primary melanoma tumor could contribute to the metastatic...

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Identifiers

PMID: 24613454
DOI: 10.1016/j.bbadis.2014.02.013

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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