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Article

RAGE Signaling in Melanoma Tumors.

International journal of molecular sciences - 26 Nov 2020

Olaoba Olamide T, Kadasah Sultan, Vetter Stefan W, Leclerc Estelle

Abstract excerpt

Despite recent progresses in its treatment, malignant cutaneous melanoma remains a cancer with very poor prognosis. Emerging evidences suggest that the receptor for advance glycation end products (RAGE) plays a key role in melanoma progression through its activation in both cancer and stromal cells. In tumors, RAGE activation is fueled by numerous ligands, S100B and HMGB1 being the most notable, but the role of...

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Identifiers

PMID: 33256110
DOI: 10.3390/ijms21238989
PMCID: PMC7730603

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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