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Article

Molecular characterization of the complement C1q, C2 and C4 genes in Brazilian patients with juvenile systemic lupus erythematosus.

Clinics (Sao Paulo, Brazil) - 1 Mar 2015

Liphaus Bernadete L, Umetsu Natalia, Jesus Adriana A, Bando Silvia Y, Silva Clovis A, Carneiro-Sampaio Magda

Abstract excerpt

OBJECTIVE: To perform a molecular characterization of the C1q, C2 and C4 genes in patients with juvenile systemic lupus erythematosus. METHODS: Patient 1 (P1) had undetectable C1q, patient 2 (P2) and patient 3 (P3) had decreased C2 and patient 4 (P4) had decreased C4 levels. All exons and non-coding regions of the C1q and C2 genes were sequenced. Mononuclear cells were cultured and stimulated with interferon...

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Identifiers

PMID: 26017655
DOI: 10.6061/clinics/2015(03)12
PMCID: PMC4449463

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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