Article
C1q: its functions within the innate and adaptive immune responses and its role in lupus autoimmunity.
The Journal of investigative dermatology - 1 Jul 2005
Sontheimer Richard D, Racila Emil, Racila Doina M
Abstract excerpt
The complement cascade is a multi-faced effector component of the innate immune response. C1q is the recognition component of the classical pathway of complement activation. In addition, C1q has been recognized to serve a number of other biological functions including a modulating role on cellular functions within the adaptive immune response. The importance of C1q to normal immune regulation is reflected by the...
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