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Article

C4A deficiency due to a 2 bp insertion is increased in patients with systemic lupus erythematosus.

The Journal of rheumatology - 1 Oct 1999

Sullivan K E, Kim N A, Goldman D, Petri M A

Abstract excerpt

OBJECTIVE: The association of C4A deficiency with systemic lupus erythematosus (SLE) is well documented. In Caucasian populations, the most common cause of C4A deficiency is a large gene deletion in linkage disequilibrium with a conserved MHC haplotype. Because of this linkage disequilibrium, it has been difficult to determine which of the genes constitutes the disease susceptibility allele. Evidence from...

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Identifiers

PMID: 10529130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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C4A deficiency due to a 2 bp insertion is increased in patients with systemic lupus erythematosus.PMID 10529130Read ↗

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