Article
Genome-wide association study with 1000 genomes imputation identifies signals for nine sex hormone-related phenotypes.
European journal of human genetics : EJHG - 1 Feb 2016
Ruth Katherine S, Campbell Purdey J, Chew Shelby, Lim Ee Mun, Hadlow Narelle, Stuckey Bronwyn G A, Brown Suzanne J, Feenstra Bjarke, Joseph John, Surdulescu Gabriela L, Zheng Hou Feng, Richards J Brent, Murray Anna, Spector Tim D, Wilson Scott G, Perry John R B
Abstract excerpt
Genetic factors contribute strongly to sex hormone levels, yet knowledge of the regulatory mechanisms remains incomplete. Genome-wide association studies (GWAS) have identified only a small number of loci associated with sex hormone levels, with several reproductive hormones yet to be assessed. The aim of the study was to identify novel genetic variants contributing to the regulation of sex hormones. We performed...
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