Article
Genome-wide association study of sex hormones, gonadotropins and sex hormone-binding protein in Chinese men.
Journal of medical genetics - 1 Dec 2013
Chen Zhuo, Tao Sha, Gao Yong, Zhang Ju, Hu Yanling, Mo Linjian, Kim Seong-Tae, Yang Xiaobo, Tan Aihua, Zhang Haiying, Qin Xue, Li Li, Wu Yongming, Zhang Shijun, Zheng S Lilly, Xu Jianfeng, Mo Zengnan, Sun Jielin
Abstract excerpt
BACKGROUND: Sex hormones and gonadotropins exert a wide variety of effects in physiological and pathological processes. Accumulated evidence shows a strong heritable component of circulating concentrations of these hormones. Recently, several genome-wide association studies (GWASs) conducted in Caucasians have identified multiple loci that influence serum levels of sex hormones. However, the genetic determinants...
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