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Article

Matrix metalloproteinase-9 polymorphism 1562 C > T (rs3918242) associated with protection against placental malaria.

The American journal of tropical medicine and hygiene - 1 Jul 2015

Apoorv Thittayil Suresh, Babu Phanithi Prakash, Meese Stefanie, Gai Prabhanjan P, Bedu-Addo George, Mockenhaupt Frank P

Abstract excerpt

Phagocytosis of malaria pigment (hemozoin) induces increased activity of matrix metalloproteinase (MMP)-9, an endopeptidase involved in cytokine regulation. In this study, we examined whether a common functional MMP-9 promoter polymorphism (rs3918242) affects Plasmodium falciparum infection in pr...

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Identifiers

PMID: 26013370
DOI: 10.4269/ajtmh.14-0816
PMCID: PMC4497894

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26013370-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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