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Article

MiRNA-146a polymorphism increases the odds of malaria in pregnancy

14 Jan 2019

Abstract excerpt

BACKGROUND: Plasmodium falciparum infection during pregnancy is a major cause of poor maternal health, adverse foetal outcome and infant mortality in sub-Saharan Africa. Genetic disposition is involved in susceptibility to malaria in pregnancy and its manifestation. MicroRNAs (miRNAs) influence gene regulation including that of innate immune responses. A miRNA-146a rs2910164 G > C single nucleotide polymorphism...

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PMID: 30642347
DOI: 10.1186/s12936-019-2643-z

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