Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A large-scale screen reveals genes that mediate electrotaxis in Dictyostelium discoideum.

Science signaling - 26 May 2015

Gao Runchi, Zhao Siwei, Jiang Xupin, Sun Yaohui, Zhao Sanjun, Gao Jing, Borleis Jane, Willard Stacey, Tang Ming, Cai Huaqing, Kamimura Yoichiro, Huang Yuesheng, Jiang Jianxin, Huang Zunxi, Mogilner Alex, Pan Tingrui, Devreotes Peter N, Zhao Min

Abstract excerpt

Directional cell migration in an electric field, a phenomenon called galvanotaxis or electrotaxis, occurs in many types of cells, and may play an important role in wound healing and development. Small extracellular electric fields can guide the migration of amoeboid cells, and we established a large-scale screening approach to search for mutants with electrotaxis phenotypes from a collection of 563 Dictyostelium...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dictyostelium
Share to Gene Knockdown Techniques

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mechanistic Target of Rapamycin Complex 2

Share to Multiprotein Complexes

Share to Proto-Oncogene Proteins c-akt

Share to Protozoan Proteins

Share to Signal Transduction

Share to TOR Serine-Threonine Kinases

Source

Open in PubMed Open full text

Identifiers

PMID: 26012633
DOI: 10.1126/scisignal.aab0562
PMCID: PMC4470479

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A large-scale screen reveals genes that mediate electrotaxis in Dictyostelium discoideum.PMID 26012633Read ↗

Genetic analysis of the role of G protein-coupled receptor signaling in electrotaxis.Semantic proximity Read ↗

TOR complex 2 integrates cell movement during chemotaxis and signal relay in Dictyostelium.Semantic proximity Read ↗

tsunami, the Dictyostelium homolog of the Fused kinase, is required for polarization and chemotaxis.Semantic proximity Read ↗

An unconventional myosin required for cell polarization and chemotaxis.Semantic proximity Read ↗

Influx of extracellular Ca2+ is necessary for electrotaxis in Dictyostelium.Semantic proximity Read ↗

Dictyostelium discoideum as a Model for Investigating Neurodegenerative DiseasesSemantic proximity Read ↗

Assessment of development and chemotaxis in Dictyostelium discoideum mutants.Semantic proximity Read ↗

Evidence of an evolutionarily conserved LMBR1 domain-containing protein that associates with endocytic cups and plays a role in cell migration in dictyostelium discoideum.Semantic proximity Read ↗

Rapid and efficient genetic engineering of both wild type and axenic strains of Dictyostelium discoideum.Semantic proximity Read ↗

A new HECT ubiquitin ligase regulating chemotaxis and development in Dictyostelium discoideum.Semantic proximity Read ↗

PIP₃-dependent macropinocytosis is incompatible with chemotaxis.Semantic proximity Read ↗

Genetics of phototaxis in a model eukaryote, Dictyostelium discoideum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.