Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Frequency and association of mitochondrial genetic variants with neurological disorders.

Mitochondrion - 1 May 2019

Cruz Ana Carolina P, Ferrasa Adriano, Muotri Alysson R, Herai Roberto H

Abstract excerpt

Mitochondria are small cytosolic organelles and the main source of energy production for the cells, especially in the brain. This organelle has its own genome, the mitochondrial DNA (mtDNA), and genetic variants in this molecule can alter the normal energy metabolism in the brain, contributing to the development of a wide assortment of Neurological Disorders (ND), including neurodevelopmental syndromes,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to DNA, Mitochondrial
Share to Genetic Predisposition to Disease
Share to Genetic Variation

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Nervous System Diseases

Source

Identifiers

PMID: 30218715
DOI: 10.1016/j.mito.2018.09.005

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Frequency and association of mitochondrial genetic variants with neurological disorders.PMID 30218715Read ↗

Neurologic disorders due to mitochondrial DNA mutations.Semantic proximity Read ↗

Mitochondrial DNA Variants in Autism Spectrum Disorder: A Systematic ReviewSemantic proximity Read ↗

Mutations that affect mitochondrial functions and their association with neurodegenerative diseasesSemantic proximity Read ↗

Comprehensive summary of mitochondrial DNA alterations in the postmortem human brain: A systematic review.Semantic proximity Read ↗

Novel potentially pathogenic variants detected in genes causing intellectual disability and epilepsy in Polish families.Semantic proximity Read ↗

The role of germline and somatic nuclear and mitochondrial DNA variation in neurodegenerative disordersSemantic proximity Read ↗

Analysis of mitochondrial DNA sequences in childhood encephalomyopathies reveals new disease-associated variants.Semantic proximity Read ↗

Mechanism and Clinical Application Prospects of Mitochondrial DNA Single Nucleotide Polymorphism in Neurodegenerative Diseases.Semantic proximity Read ↗

Mitochondrial mutations: newly discovered players in neuronal degeneration.Semantic proximity Read ↗

Parkinson's Disease, Parkinsonisms, and Mitochondria: the Role of Nuclear and Mitochondrial DNA.Semantic proximity Read ↗

A catalog of homoplasmic and heteroplasmic mitochondrial DNA variants in humansSemantic proximity Read ↗

Neurological diseases due to mitochondrial DNA mutations: concepts and problems in pathogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.