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Article

Connecting Anxiety and Genomic Copy Number Variation: A Genome-Wide Analysis in CD-1 Mice.

PloS one - 1 Jan 2015

Brenndörfer Julia, Altmann André, Widner-Andrä Regina, Pütz Benno, Czamara Darina, Tilch Erik, Kam-Thong Tony, Weber Peter, Rex-Haffner Monika, Bettecken Thomas, Bultmann Andrea, Müller-Myhsok Bertram, Binder Elisabeth E, Landgraf Rainer, Czibere Ludwig

Abstract excerpt

Genomic copy number variants (CNVs) have been implicated in multiple psychiatric disorders, but not much is known about their influence on anxiety disorders specifically. Using next-generation sequencing (NGS) and two additional array-based genotyping approaches, we detected CNVs in a mouse model consisting of two inbred mouse lines showing high (HAB) and low (LAB) anxiety-related behavior, respectively. An...

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Identifiers

PMID: 26011321
DOI: 10.1371/journal.pone.0128465
PMCID: PMC4444327

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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