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Extreme differences in SLCO1B3 functional polymorphisms in Roma and Hungarian populations.

Environmental toxicology and pharmacology - 1 May 2015

Nagy Agnes, Szalai Renata, Magyari Lili, Bene Judit, Toth Kalman, Melegh Bela

Abstract excerpt

Variants in SLCO1B3 transporter are linked to disposition and uptake of drugs and show high degree of heterogeneity between populations. A total of 467 Roma and 448 Hungarian subjects were genotyped for SLCO1B3 c.334T>G and c.1683-5676A>G variant alleles by PCR-RFLP assay and direct sequencing. We found significant differences in the frequencies of homozygous variant genotypes of SLCO1B3 334GG (41.54% vs. 8.04%,...

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PMID: 26005078
DOI: 10.1016/j.etap.2015.04.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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