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Article

Marked differences in frequencies of statin therapy relevant SLCO1B1 variants and haplotypes between Roma and Hungarian populations.

BMC genetics - 3 Sept 2015

Nagy Agnes, Sipeky Csilla, Szalai Renata, Melegh Bela Imre, Matyas Petra, Ganczer Alma, Toth Kalman, Melegh Bela

Abstract excerpt

BACKGROUND: SLCO1B1 polymorphisms are relevant in statin pharmacokinetics. Aim of this study was to investigate the genetic variability and haplotype profile of SLCO1B1 polymorphisms in Roma and Hungarian populations. Genotypes of 470 Roma and 442 Hungarian subjects for c.388A > G, c.521T > C and c.1498-1331T > C polymorphisms were determined by PCR-RFLP assay. Using these SNPs eight different haplotypes could be...

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Identifiers

PMID: 26334733
DOI: 10.1186/s12863-015-0262-4
PMCID: PMC4559300

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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