Article
Genetic Risk Score for Essential Hypertension and Risk of Preeclampsia.
American journal of hypertension - 1 Jan 2016
Smith Caitlin J, Saftlas Audrey F, Spracklen Cassandra N, Triche Elizabeth W, Bjonnes Andrew, Keating Brendan, Saxena Richa, Breheny Patrick J, Dewan Andrew T, Robinson Jennifer G, Hoh Josephine, Ryckman Kelli K
Abstract excerpt
BACKGROUND: Preeclampsia is a hypertensive complication of pregnancy characterized by novel onset of hypertension after 20 weeks gestation, accompanied by proteinuria. Epidemiological evidence suggests that genetic susceptibility exists for preeclampsia; however, whether preeclampsia is the result of underlying genetic risk for essential hypertension has yet to be investigated. Based on the hypertensive state...
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