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Article

Long-term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores.

Acta obstetricia et gynecologica Scandinavica - 1 Oct 2025

Kivioja Anna, Tyrmi Jaakko, Toivonen Elli, Huhtala Heini, Jääskeläinen Tiina, Kettunen Johannes, Saarela Tanja, Laivuori Hannele

Abstract excerpt

INTRODUCTION: The association between preeclampsia (PE) and an elevated risk of cardiovascular disease (CVD) is well documented. Recent genome-wide association studies of PE have further highlighted their possible common genetic background. We investigated how the history of hypertensive disorders of pregnancy (HDP), including the PE phenotype, and normotensive pregnancy, combined with polygenic risk scores...

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Identifiers

PMID: 40746022
DOI: 10.1111/aogs.70021
PMCID: PMC12451206

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