Article
Increased Risk of Preeclampsia in Women With a Genetic Predisposition to Elevated Blood Pressure.
Hypertension (Dallas, Tex. : 1979) - 1 Sept 2022
Kivioja Anna, Toivonen Elli, Tyrmi Jaakko, Ruotsalainen Sanni, Ripatti Samuli, Huhtala Heini, Jääskeläinen Tiina, Heinonen Seppo, Kajantie Eero, Kere Juha, Kivinen Katja, Pouta Anneli, Saarela Tanja, Laivuori Hannele
Abstract excerpt
BACKGROUND: Preeclampsia causes significant maternal and perinatal morbidity. Genetic factors seem to affect the onset of the disease. We aimed to investigate whether the polygenic risk score for blood pressure (BP; BP-PRS) is associated with preeclampsia, its subtypes, and BP values during pregnancy. METHODS: The analyses were performed in the FINNPEC study (Finnish Genetics of Pre-Eclampsia Consortium) cohort...
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