Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Associations of polygenic risk scores for preeclampsia and blood pressure with hypertensive disorders of pregnancy.

Journal of hypertension - 1 Mar 2023

Nurkkala Jouko, Kauko Anni, FinnGen, Laivuori Hannele, Saarela Tanja, Tyrmi Jaakko S, Vaura Felix, Cheng Susan, Bello Natalie A, Aittokallio Jenni, Niiranen Teemu

Abstract excerpt

BACKGROUND: Preexisting hypertension increases risk for preeclampsia. We examined whether a generic blood pressure polygenic risk score (BP-PRS), compared with a preeclampsia-specific polygenic risk score (PE-PRS), could better predict hypertensive disorders of pregnancy. METHODS: Our study sample included 141 298 genotyped FinnGen study participants with at least one childbirth and followed from 1969 to 2021. We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood Pressure
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypertension, Pregnancy-Induced

Share to Polymorphism, Single Nucleotide

Share to Pre-Eclampsia

Share to Pregnancy

Share to Pregnancy and preeclampsia studies

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 36947680
DOI: 10.1097/HJH.0000000000003336
PMCID: PMC9894151

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Associations of polygenic risk scores for preeclampsia and blood pressure with hypertensive disorders of pregnancy.PMID 36947680Read ↗

Polygenic Risk Scores for Preeclampsia Prediction Beyond Gold-Standard Clinical Models in Multiethnic Populations.Semantic proximity Read ↗

Genetic predictors of blood pressure traits are associated with preeclampsia.Semantic proximity Read ↗

Genetic Risk Factors Associated With Preeclampsia and Hypertensive Disorders of PregnancySemantic proximity Read ↗

Prediction of Preeclampsia from Clinical and Genetic Risk Factors in Early and Late Pregnancy Using Machine Learning and Polygenic Risk ScoresSemantic proximity Read ↗

Preeclampsia prediction with maternal and paternal polygenic risk scores: the TMM BirThree Cohort StudySemantic proximity Read ↗

Preeclampsia Prediction Using Machine Learning and Polygenic Risk Scores From Clinical and Genetic Risk Factors in Early and Late PregnanciesSemantic proximity Read ↗

Long-term cardiovascular risk in women with hypertensive disorders of pregnancy: Insights from polygenic risk scores.Semantic proximity Read ↗

Genetic Predictors of Blood Pressure Traits are Associated with PreeclampsiaSemantic proximity Read ↗

Polygenic Risk Scores Predict Hypertension Onset and Cardiovascular Risk.Semantic proximity Read ↗

Increased Risk of Preeclampsia in Women With a Genetic Predisposition to Elevated Blood Pressure.Semantic proximity Read ↗

Preeclampsia prediction with maternal and paternal polygenic risk scores: the TMM BirThree Cohort StudySemantic proximity Read ↗

Preeclampsia, gestational hypertension, and cardiovascular disease risk: a genetic epidemiological studySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.