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Article

Absence-like seizures and their pharmacological profile in tottering-6j mice.

Biochemical and biophysical research communications - 1 Jan 2000

Kim Tae Yeon, Maki Takehiro, Zhou Ying, Sakai Keita, Mizuno Yuri, Ishikawa Akiyoshi, Tanaka Ryo, Niimi Kimie, Li Weidong, Nagano Norihiro, Takahashi Eiki

Abstract excerpt

We previously showed that recessive ataxic tottering-6j mice carried a base substitution (C-to-A) in the consensus splice acceptor sequence linked to exon 5 of the α1 subunit of the Cav2.1 channel gene (Cacna1a), resulting in the skipping of exon 5 and deletion of part of the S4-S5 linker, S5, and part of the S5-S6 linker in domain I of the α1 subunit of the Cav2.1 channel. However, the electrophysiological and...

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Identifiers

PMID: 26002462
DOI: 10.1016/j.bbrc.2015.05.050

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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