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Article

New ataxic tottering-6j mouse allele containing a Cacna1a gene mutation.

PloS one - 1 Jan 2012

Li Weidong, Zhou Ying, Tian Xiaoli, Kim Tae Yeon, Ito Namiko, Watanabe Kaori, Tsuji Akiko, Niimi Kimie, Aoyama Yo, Arai Takashi, Takahashi Eiki

Abstract excerpt

Voltage-gated Ca(2+) (Ca(v)) channels control neuronal functions including neurotransmitter release and gene expression. The Cacna1a gene encodes the α1 subunit of the pore-forming Ca(v)2.1 channel. Mice with mutations in this gene form useful tools for defining channel functions. The recessive a...

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Identifiers

PMID: 22952933
DOI: 10.1371/journal.pone.0044230
PMCID: PMC3432086

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22952933-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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