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Article

Explicit Modeling of Ancestry Improves Polygenic Risk Scores and BLUP Prediction.

Genetic epidemiology - 1 Sept 2015

Chen Chia-Yen, Han Jiali, Hunter David J, Kraft Peter, Price Alkes L

Abstract excerpt

Polygenic prediction using genome-wide SNPs can provide high prediction accuracy for complex traits. Here, we investigate the question of how to account for genetic ancestry when conducting polygenic prediction. We show that the accuracy of polygenic prediction in structured populations may be pa...

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Identifiers

PMID: 25995153
DOI: 10.1002/gepi.21906
PMCID: PMC4734143

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25995153-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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