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Article

Cumulative role of rare and common putative functional genetic variants at NPAS3 in schizophrenia susceptibility.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Oct 2015

González-Peñas Javier, Arrojo Manuel, Paz Eduardo, Brenlla Julio, Páramo Mario, Costas Javier

Abstract excerpt

Schizophrenia may be considered a human-specific disorder arisen as a maladaptive by-product of human-specific brain evolution. Therefore, genetic variants involved in susceptibility to schizophrenia may be identified among those genes related to acquisition of human-specific traits. NPAS3, a transcription factor involved in central nervous system development and neurogenesis, seems to be implicated in the...

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Source

Identifiers

PMID: 25982957
DOI: 10.1002/ajmg.b.32324

Genes

NPAS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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