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Article

Revisiting Schizophrenia from an Evolutionary Perspective: An Association Study of Recent Evolutionary Markers and Schizophrenia.

Schizophrenia bulletin - 29 Apr 2021

Bhattacharyya Upasana, Deshpande Smita N, Bhatia Triptish, Thelma B K

Abstract excerpt

The persistence of schizophrenia in human populations at a high prevalence and with a large heritability estimate despite reduced fertility and increased mortality rate is a Darwinian paradox. This may be likely if the genomic components that predispose to schizophrenia are also advantageous for the acquisition of important human traits, such as language and cognition. Accordingly, an emerging group of genomic...

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PMID: 33350444
DOI: 10.1093/schbul/sbaa179
PMCID: PMC8759809

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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