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Article

Neuropeptide S reduces mouse aggressiveness in the resident/intruder test through selective activation of the neuropeptide S receptor.

Neuropharmacology - 1 Oct 2015

Ruzza Chiara, Asth Laila, Guerrini Remo, Trapella Claudio, Gavioli Elaine C

Abstract excerpt

Neuropeptide S (NPS) regulates various biological functions by selectively activating the NPS receptor (NPSR). In particular NPS evokes robust anxiolytic-like effects in rodents together with a stimulant and arousal promoting action. The aim of the study was to investigate the effects of NPS on the aggressiveness of mice subjected to the resident/intruder test. Moreover the putative role played by the endogenous...

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Source

Identifiers

PMID: 25979487
DOI: 10.1016/j.neuropharm.2015.05.002

Genes

NPS

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