Article
Behavioural phenotypic characterization of CD-1 mice lacking the neuropeptide S receptor.
Neuropharmacology - 1 Apr 2012
Ruzza C, Pulga A, Rizzi A, Marzola G, Guerrini R, Calo' G
Abstract excerpt
Neuropeptide S (NPS) is the endogenous ligand of a previously orphan receptor now named NPSR. In the brain NPS regulates several biological functions including anxiety, arousal, locomotion, food intake, learning and memory, pain and drug abuse. Mice lacking the NPSR gene (NPSR(-/-)) represent an useful tool to investigate the neurobiology of the NPS/NPSR system. NPSR(-/-) mice have been generated in a 129S6/SvEv...
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