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Article

Neuropeptide S alters anxiety, but not depression-like behaviour in Flinders Sensitive Line rats: a genetic animal model of depression.

The international journal of neuropsychopharmacology - 1 Apr 2012

Wegener Gregers, Finger Beate C, Elfving Betina, Keller Kirsten, Liebenberg Nico, Fischer Christina W, Singewald Nicolas, Slattery David A, Neumann Inga D, Mathé Aleksander A

Abstract excerpt

Neuropeptide S (NPS) and its receptor (NPSR) have been implicated in the mediation of anxiolytic-like behaviour in rodents. However, little knowledge is available regarding the NPS system in depression-related behaviours, and whether NPS also exerts anxiolytic effects in an animal model of psychopathology. Therefore, the aim of this work was to characterize the effects of NPS on depression- and anxiety-related...

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Source

Identifiers

PMID: 21708052
DOI: 10.1017/S1461145711000678

Genes

NPS
FST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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