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Article

Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours.

European journal of cancer (Oxford, England : 1990) - 1 Feb 2014

Bate-Eya Laurel T, Ebus Marli E, Koster Jan, den Hartog Ilona J M, Zwijnenburg Danny A, Schild Linda, van der Ploeg Ida, Dolman M Emmy M, Caron Huib N, Versteeg Rogier, Molenaar Jan J

Abstract excerpt

Recently protocols have been devised for the culturing of cell lines from fresh tumours under serum-free conditions in defined neural stem cell medium. These cells, frequently called tumour initiating cells (TICs) closely retained characteristics of the tumours of origin. We report the isolation of eight newly-derived neuroblastoma TICs from six primary neuroblastoma tumours and two bone marrow metastases. The...

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Identifiers

PMID: 24321263
DOI: 10.1016/j.ejca.2013.11.015

Genes

MYCN
CHGA
DBH

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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