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Article

Neuroblastoma cells isolated from bone marrow metastases contain a naturally enriched tumor-initiating cell.

Cancer research - 1 Dec 2007

Hansford Loen M, McKee Amy E, Zhang Libo, George Rani E, Gerstle J Ted, Thorner Paul S, Smith Kristen M, Look A Thomas, Yeger Herman, Miller Freda D, Irwin Meredith S, Thiele Carol J, Kaplan David R

Abstract excerpt

Neuroblastoma is a heterogeneous pediatric tumor thought to arise from the embryonic neural crest. Identification of the cell responsible for propagating neuroblastomas is essential to understanding this often recurrent, rapidly progressing disease. We have isolated and characterized putative tumor-initiating cells from 16 tumors and bone marrow metastases from patients in all neuroblastoma risk groups....

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Identifiers

PMID: 18056449
DOI: 10.1158/0008-5472.CAN-07-0718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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