Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumours

21 Oct 2019

Abstract excerpt

BACKGROUND: Neuroblastoma (NB) is a paediatric tumour of the sympathetic nervous system. Half of all cases are defined high-risk with an overall survival less than 40% at 5 years from diagnosis. The lack of in vitro models able to recapitulate the intrinsic heterogeneity of primary NB tumours has hindered progress in understanding disease pathogenesis and therapy response. METHODS: Here we describe the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cellular Mechanics and Interactions
Share to Glioma Diagnosis and Treatment
Share to Neuroblastoma Research and Treatments

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31638925
DOI: 10.1186/s12885-019-6149-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patient-derived organoids (PDOs) as a novel in vitro model for neuroblastoma tumoursPMID 31638925Read ↗

Neuroblastoma patient-derived orthotopic xenografts retain metastatic patterns and geno- and phenotypes of patient tumours.Semantic proximity Read ↗

Newly-derived neuroblastoma cell lines propagated in serum-free media recapitulate the genotype and phenotype of primary neuroblastoma tumours.Semantic proximity Read ↗

Joint single-cell genetic and transcriptomic analysis reveal pre-malignant SCP-like subclones in human neuroblastomaSemantic proximity Read ↗

Descriptive analysis of tumor cells with stem like phenotypes in metastatic and benign adrenal tumors.Semantic proximity Read ↗

An overview of neuroblastoma cell lineage phenotypes and in vitro models.Semantic proximity Read ↗

The neuroblastoma tumor microenvironment: From an in-depth characterization towards novel therapiesSemantic proximity Read ↗

Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cellSemantic proximity Read ↗

Exploration of the Molecular Mechanism of Intercellular Communication in Paediatric Neuroblastoma by Single-Cell SequencingSemantic proximity Read ↗

Single-nuclei transcriptomes from human adrenal gland reveals distinct cellular identities of low and high-risk neuroblastoma tumorsSemantic proximity Read ↗

Mechanisms involved in selecting and maintaining neuroblastoma cancer stem cell populations, and perspectives for therapeutic targetingSemantic proximity Read ↗

Establishment and phenotyping of neurosphere cultures from primary neuroblastoma samplesSemantic proximity Read ↗

Single-nuclei transcriptomes from human adrenal gland reveal distinct cellular identities of low and high-risk neuroblastoma tumorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.