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Article

Clinical Relevance of Tumor Cells with Stem-Like Properties in Pediatric Brain Tumors

28 Jan 2011

Abstract excerpt

BACKGROUND: Primitive brain tumors are the leading cause of cancer-related death in children. Tumor cells with stem-like properties (TSCs), thought to account for tumorigenesis and therapeutic resistance, have been isolated from high-grade gliomas in adults. Whether TSCs are a common component of pediatric brain tumors and are of clinical relevance remains to be determined. METHODOLOGY/PRINCIPAL FINDINGS: Tumor...

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PMID: 21297991
DOI: 10.1371/journal.pone.0016375

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