Article
Association of a neurokinin 3 receptor polymorphism with the anterior basal forebrain.
Neurobiology of aging - 1 Jun 2015
Teipel Stefan J, Grothe Michel J, Wittfeld Katharina, Hoffmann Wolfgang, Hegenscheid Katrin, Völzke Henry, Homuth Georg, Grabe Hans J
Abstract excerpt
The neuropeptide neurokinin 3 (NK3) and its receptor modulate cholinergic activity of the basal forebrain (BF) and are implicated in learning and memory. In Alzheimer's disease, the rs2765 single-nucleotide polymorphism (SNP) of the NK3 receptor-coding gene TACR3 was correlated with the right hip...
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