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Article

Neurokinin3 receptor as a target to predict and improve learning and memory in the aged organism.

Proceedings of the National Academy of Sciences of the United States of America - 10 Sept 2013

de Souza Silva Maria A, Lenz Bernd, Rotter Andrea, Biermann Teresa, Peters Oliver, Ramirez Alfredo, Jessen Frank, Maier Wolfgang, Hüll Michael, Schröder Johannes, Frölich Lutz, Teipel Stefan, Gruber Oliver, Kornhuber Johannes, Huston Joseph P, Müller Christian P, Schäble Sandra

Abstract excerpt

Impaired learning and memory performance is often found in aging as an early sign of dementia. It is associated with neuronal loss and reduced functioning of cholinergic networks. Here we present evidence that the neurokinin3 receptors (NK3-R) and their influence on acetylcholine (ACh) release ma...

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Identifiers

PMID: 23983264
DOI: 10.1073/pnas.1306884110
PMCID: PMC3773732

Genes

TACR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23983264-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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