Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Choline Acetyltransferase (CHAT) Gene is Associated with Parahippocampal and Hippocampal Structure and Short-term Memory Span.

Neuroscience - 15 Jan 2018

Zhu Bi, Chen Chuansheng, Moyzis Robert K, Dong Qi, Lin Chongde

Abstract excerpt

The CHAT gene encodes choline acetyltransferase, which is an enzyme responsible for the biosynthesis of the neurotransmitter acetylcholine in the brain. This study collected structural MRI, genetic, and behavioral data from 324 healthy Chinese adults, and examined the associations between CHAT genetic variants, parahippocampal and hippocampal structure, and short-term memory span. After controlling for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Asian People
Share to Choline O-Acetyltransferase

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Association Studies

Share to Hippocampus

Share to Linkage Disequilibrium

Share to Magnetic Resonance Imaging

Share to Memory, Short-Term

Share to Organ Size

Source

Identifiers

PMID: 29170094
DOI: 10.1016/j.neuroscience.2017.11.021

Genes

CHAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Choline Acetyltransferase (CHAT) Gene is Associated with Parahippocampal and Hippocampal Structure and Short-term Memory Span.PMID 29170094Read ↗

Association of Choline Acetyltransferase Gene Polymorphisms (SNPs rs868750G/A, rs1880676G/A, rs2177369G/A and rs3810950G/A) with Alzheimer's Disease Risk: A Meta-Analysis.Semantic proximity Read ↗

Interaction of COMT and KIBRA modulates the association between hippocampal structure and episodic memory performance in healthy young adults.Semantic proximity Read ↗

Genetic variation in the choline acetyltransferase (CHAT) gene may be associated with the risk of Alzheimer's disease.Semantic proximity Read ↗

Genetic variants in the choline acetyltransferase (ChAT) gene are modestly associated with normal cognitive function in the elderly.Semantic proximity Read ↗

Polymorphic variation in CHAT gene modulates general cognitive ability: An association study with random student cohort.Semantic proximity Read ↗

A genome-wide survey of human short-term memory.Semantic proximity Read ↗

Cholinergic-estrogen interaction underpins the effect of education on attenuating cognitive sex differences in a Thai healthy populationSemantic proximity Read ↗

The NTSR1 gene modulates the association between hippocampal structure and working memory performance.Semantic proximity Read ↗

Choline acetyltransferase 2384G>a polymorphism and the risk of Alzheimer disease.Semantic proximity Read ↗

Genetic Association of CHAT rs3810950 and rs2177369 Polymorphisms with the Risk of Alzheimer's Disease: A Meta-Analysis.Semantic proximity Read ↗

Association of a neurokinin 3 receptor polymorphism with the anterior basal forebrain.Semantic proximity Read ↗

Genetic variation in the choline O-acetyltransferase gene in depression and Alzheimer's disease: the VITA and Milano studies.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.