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Article

Nuclear maspin expression correlates with the CpG island methylator phenotype and tumor aggressiveness in colorectal cancer.

International journal of clinical and experimental pathology - 1 Jan 2015

Kim Jung Ho, Cho Nam-Yun, Bae Jeong Mo, Kim Kyung-Ju, Rhee Ye-Young, Lee Hye Seung, Kang Gyeong Hoon

Abstract excerpt

It has been suggested that nuclear expression of maspin (mammary serine protease inhibitor; also known as SERPINB5) in colorectal cancer (CRC) is associated with proximal colonic tumor location, mucinous and poorly differentiated histology, microsatellite instability-high (MSI-H), and poor progno...

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Source

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Identifiers

PMID: 25973084
PMCID: PMC4396253

Genes

CRABP1
IGF2
MLH1
NEUROG1
RUNX3
SERPINB5
SOCS1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25973084-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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