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Article

Neuropeptide S receptor gene variation and neural correlates of cognitive emotion regulation.

Social cognitive and affective neuroscience - 1 Dec 2015

Guhn Anne, Domschke Katharina, Müller Laura D, Dresler Thomas, Eff Florian, Kopf Juliane, Deckert Jürgen, Reif Andreas, Herrmann Martin J

Abstract excerpt

The neuropeptide S (NPS) and its receptor NPSR have captured attention in the pathogenesis of anxiety disorders. Here, a functional polymorphism in the NPSR1 gene has been linked to deviant cortico-limbic interactions in response to negative stimuli. While healthy T allele carriers exhibited increased amygdala and prefrontal cortex activity, panic disorder patients carrying the T risk allele displayed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25971599
DOI: 10.1093/scan/nsv061
PMCID: PMC4666111

Genes

NPS
NPSR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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