Interaction of the neuropeptide S receptor gene Asn¹⁰⁷Ile variant and environment: contribution to affective and anxiety disorders, and suicidal behaviour.

doi:10.1017/S1461145713001478

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Article

Interaction of the neuropeptide S receptor gene Asn¹⁰⁷Ile variant and environment: contribution to affective and anxiety disorders, and suicidal behaviour.

The international journal of neuropsychopharmacology - 1 Apr 2014

Laas Kariina, Reif Andreas, Akkermann Kirsti, Kiive Evelyn, Domschke Katharina, Lesch Klaus-Peter, Veidebaum Toomas, Harro Jaanus

Abstract excerpt

Neuropeptide S is involved in anxiety and arousal modulation, and the functional polymorphism Asn107Ile (rs324981, A > T) of the neuropeptide S receptor gene (NPSR1) is associated with panic disorder and anxiety/fear-related traits. NPSR1 also interacts with the environment in shaping personality and impulsivity. We therefore examined whether the NPSR1 A/T polymorphism is associated with affective and anxiety...

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PMID: 24331455
DOI: 10.1017/S1461145713001478

Genes

NPSR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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