Neuropeptide S receptor gene: fear-specific modulations of prefrontal activation.

doi:10.1016/j.neuroimage.2012.10.033

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Article

Neuropeptide S receptor gene: fear-specific modulations of prefrontal activation.

NeuroImage - 1 Feb 2013

Tupak Sara V, Reif Andreas, Pauli Paul, Dresler Thomas, Herrmann Martin J, Domschke Katharina, Jochum Clara, Haas Elisabeth, Baumann Christian, Weber Heike, Fallgatter Andreas J, Deckert Jürgen, Ehlis Ann-Christine

Abstract excerpt

Since central administration of neuropeptide S (NPS) has been shown to exert anxiolytic effects on rodent behavior in a number of studies, genetic variants of its cognate G-protein coupled receptor (NPSR1) became the focus of several recent human studies on anxiety and anxiety disorders. The T allele of rs324981, which goes along with enhanced receptor function, was associated with panic disorder, increased...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Share to Receptors, G-Protein-Coupled

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Source

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Identifiers

PMID: 23103692
DOI: 10.1016/j.neuroimage.2012.10.033

Genes

NPSR1
NPS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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