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Article

Bone metastasis in prostate cancer: Recurring mitochondrial DNA mutation reveals selective pressure exerted by the bone microenvironment.

Bone - 1 Sept 2015

Arnold Rebecca S, Fedewa Stacey A, Goodman Michael, Osunkoya Adeboye O, Kissick Haydn T, Morrissey Colm, True Lawrence D, Petros John A

Abstract excerpt

BACKGROUND: Cancer progression and metastasis occur such that cells with acquired mutations enhancing growth and survival (or inhibiting cell death) increase in number, a concept that has been recognized as analogous to Darwinian evolution of species since Peter C. Nowell's description in 1976. S...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 25952970
DOI: 10.1016/j.bone.2015.04.046
PMCID: PMC4466124

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25952970-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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