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Article

Somatic mutations throughout the entire mitochondrial genome are associated with elevated PSA levels in prostate cancer patients.

American journal of human genetics - 10 Dec 2010

Kloss-Brandstätter Anita, Schäfer Georg, Erhart Gertraud, Hüttenhofer Alexander, Coassin Stefan, Seifarth Christof, Summerer Monika, Bektic Jasmin, Klocker Helmut, Kronenberg Florian

Abstract excerpt

The genetic etiology of prostate cancer, the most common form of male cancer in western countries, is complex and the interplay of disease genes with environmental factors is far from being understood. Studies on somatic mitochondrial DNA (mtDNA) mutations have become an important aspect of cancer research because these mutations might have functional consequences and/or might serve as biosensors for tumor...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21129724
DOI: 10.1016/j.ajhg.2010.11.001
PMCID: PMC2997360

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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