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Article

Somatic alterations contributing to metastasis of a castration-resistant prostate cancer.

Human mutation - 1 Sept 2013

Nickerson Michael L, Im Kate M, Misner Kevin J, Tan Wei, Lou Hong, Gold Bert, Wells David W, Bravo Hector C, Fredrikson Karin M, Harkins Timothy T, Milos Patrice, Zbar Berton, Linehan W Marston, Yeager Meredith, Andresson Thorkell, Dean Michael, Bova G Steven

Abstract excerpt

Metastatic castration-resistant prostate cancer (mCRPC) is a lethal disease, and molecular markers that differentiate indolent from aggressive subtypes are needed. We sequenced the exomes of five metastatic tumors and healthy kidney tissue from an index case with mCRPC to identify lesions associa...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 23636849
DOI: 10.1002/humu.22346
PMCID: PMC3745530

Genes

TET2
BRCA1
ERG
TMPRSS2
PBRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23636849-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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